The Post-Polio Syndrome: Advances in the Pathogenesis and Treatment (Annals of the New York Academy of Sciences)

By Leonard T. Kurland and International Symposium on Poliomyelitis Control

Post-polio syndrome (PPS) embodies the new neuromuscular symptoms that patients with prior paralytic poliomyelitis develop after a stable course from 20 to 40 years. These include new muscle weakness, fatigue, muscular atrophy, muscle pain and various secondary muscular complaints. Fundamental questions regarding the neurobiology of the motor neurones previously affected by the poliovirus, the ongoing changes of the reinnervating process, and the potential role of the poliovirus in generating a chronic immune stimulation or viral persistence are discussed in this volume. Data from the neurological, immunological, virological, electrophysiological and rehabilitational fields is presented, shedding light on the pathogenesis of post-polio syndrome, as well as that of other motor neurone diseases such as amyotrophic lateral sclerosis (ALS).

• Format: Hardcover
• Language: English
• ISBN: 0897669177
• ISBN13: 9780897669177
• Release Date: January 1995
• Publisher: New York Academy of Sciences
• Length: 350 Pages
• Weight: 1.70 lbs.
• Dimensions: 9.5" x 1.0" x 6.5"