Molecular and cytogenetic studies of non-disjunction: Proceedings of the Fifth Annual National Down Syndrome Society Symposium held in New York, NY, December ... in clinical and biological research)

By National Down Syndrome Society and Terry J. Hassold

Trisomy 21 is the most common genetic disorder in humans. The present volume reviews the results of molecular and cytogenetic techniques performed on four organisms--humans, mice, "Drosophila," and yeast. Examined are the association between meiotic recombination and chromosome disjunction, increasing maternal age and non-disjunction in humans, and genetic factors that may contribute to a predisposition to non-disjunction. Molecular analyses involving different human chromosomes, the importance of tissue-specific trisonomy, and the significance of specific etiological agents to non-disjunction are also considered.

• Format: Hardcover
• Language: English
• ISBN: 0845151614
• ISBN13: 9780845151617
• Release Date: January 1989
• Publisher: A.R. Liss
• Length: 360 Pages