A critical treatment of all aspects, containing definitive examples, detailed description of data handling, compilations of information on columns and column packings, and tables of important solvents and standard reference materials. Combines a basic, unified theory with practical know-how, integrating methods of gel permeation and gel filtration chromatography. Provides an understanding of molecular characterization problems as well as a background for developing new and improved characterization methods and apparatus for HPSEC performed with columns of small particles at high pressures.
Even though over 20 years old, this text remains the standard in the field of SEC. The introductory chapters on retention, band broadening, and resolution not only are a must read but will be returned to many times. The sections on instrumentation, detectors, columns, and data handling are still useful, but are dated. This book could greatly benefit from a second edition, to include updated detection and column methodologies, as well as hyphenated techniques. As such, because it is not a cheap book, it is probably not the ideal textbook. However, academics, industrial practitioners, and anyone who is seeking either basic or advanced SEC info will probably find what they need here. It should also be mentioned that the treatment of solution thermodynamics (i.e., the combined effects of solvent and temperature on dissolution and dilute solution properties) is above average for an SEC text. For a 20+ year old book, the treatment of the subject matter has held up extremely well.
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