Intramembrane-Cleaving Proteases (I-CLiPs)

by Uwe Lendeckel

In recent years a growing number of proteases have been identified that catalyse peptide bond hydrolysis in the plane of the cellular membrane. These so-called 'intramembrane-cleaving proteases' (I-CLiPs) are involved in a diverse range of cellular processes, including cell regulation, signalling, quorum sensing, protein processing, lipid metabolism and the unfolded protein response. Some I-CLiPs play critical roles in diseases such as Alzheimer's...

• Format: Hardcover
• Language: English
• ISBN: 1402063105
• ISBN13: 9781402063107
• Release Date: July 2007
• Publisher: Springer
• Length: 142 Pages
• Weight: 0.79 lbs.
• Dimensions: 0.5" x 7.4" x 9.3"