Fast Facts: Comprehensive Genomic Profiling

By Rapoport

Cancer is a multifaceted disease in which genetic changes induce uncontrolled tumor growth. Genomic characterization of cancer is now leading to better diagnostic, prognostic and predictive biomarkers, and effective individualized management. 'Fast Facts: Comprehensive Genomic Profiling' provides a crash course in the science, methods and application of genomic profiling. Assuming only the most basic knowledge - or memory - of cell biology, the authors provide an overview of DNA and RNA biology and next-generation sequencing. This sets in context the descriptions of prognostic and predictive biomarkers for different cancer types and genomic-based treatments. Finally, but importantly, some of the practicalities of gaining and interpreting genomic information are described. Whether you need a primer or a refresher, this short colorful book demystifies this complex subject. Contents: * Genetic mutations and biomarkers * Understanding next-generation sequencing * Elements of comprehensive genomic profiles * Role in precision oncology * Predictive and prognostic biomarkers * Overcoming barriers to genotype-directed therapy

• Format: Paperback
• Language: English
• ISBN: 3318068187
• ISBN13: 9783318068184
• Release Date: October 2020
• Publisher: S. Karger Publishing
• Length: 108 Pages
• Weight: 0.44 lbs.
• Dimensions: 0.2" x 8.3" x 6.0"