This comprehensive and clear text familiarizes clinicians with the most recent information concerning bone marrow failure syndromes, including anemia, leukopenia, and thombocytopenia. Twelve top experts present state-of-the-art guidance on pathophysiology and treatment, with an emphasis on chemotherapy. The result is an indispensable source on the treatment of these often life-threatening diseases.Provides a complete understanding of individual syndromes with disease-oriented chapters.Offers a comprehensive chapter on Proximal Nocturnal Hemoglobinurea, including its biological aspects a subject that has very little previous research. Emphasizes bone marrow and stem cell transplantation protocols as well as hematologic growth factors.Organizes chapters consistently to address history * epidemiology * clinical features * differential diagnosis * and treatment Includes abundant photomicrographs and diagrams to clarify complex concepts and clinical issues.Features the expertise of several members of the National Institutes of Health in Bethesda, MD a leading center for the research and treatment of these syndromes.
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