Aging and Age-Related Disorders

By Stephen Bondy

Book Overview

Chapters: General Aspects of Aging 1: Protein Redox Regulation Mechanisms in Aging 2: Nitrosative Stress in Aging 3: Intervention with Multiple Micronutrients Including Dietary and Endogenous Antioxidants for Healthy Aging 4: Advanced Glycation End Products, Rage and Aging 5: Sirtuins and Mammalian Aging 6: Estrogenic Modulation of Longevity by Induction of Antioxidant Enzymes 7: Mitochondrial Respiratory Function Decline in Aging and Lifespan Extension by Caloric Restriction 8: Methylglyoxal, Oxidative Stress, and Aging The Cardiovascular System 9: Novel Strategies for Neurovascular Longevity during Aging 10: Oxidative Stress in Vascular Disease 11: The Role of Mitochondrial Reactive Oxygen Species Formation for Aging-induced Vascular Dysfunction 12: Aging, oxidative stress and cardiovascular disorders 13: Oxidative stress, aging, and cardiovascular disease 14: Anti-Oxidation as a Prevention of Cardiovascular Diseases - An Effect of Polyphenols 15: Vascular aging and oxidative stress: hormesis and adaptive cellular pathways 16: Role of oxidative stress in mediating elevated blood pressure with aging The Nervous System 17: Melatonin, Oxidative Stress and the Aging Brain 18: The SAM strain of mice, a higher oxidative stress, age-dependent degenerative diseases and senescence acceleration model 19: Antioxidants combined with behavioral enrichment can slow brain aging 20: Role of nitric oxide in neurodegeneration and vulnerability of neuronal cells to nitric oxide metabolites and reactive oxygen species 21: Free radical-mediated damages to brain in Alzheimer's disease: Role of acrolein and preclinical promise of antioxidant polyphenols. 22: An epigenetic model for susceptibility to oxidative DNA damage in the aging brain and Alzheimer's disease

• Format: Paperback
• Language: English
• ISBN: 1617796999
• ISBN13: 9781617796999
• Release Date: November 2012
• Publisher: Humana
• Length: 472 Pages
• Weight: 1.49 lbs.
• Dimensions: 1.0" x 6.1" x 9.2"